Prenol lipids
Medchemexpress LLC Tanshinone IIA sulfonate sodium | 69659-80-9 | 396.39 | 5 MG
Tanshinone IIA sulfonate (sodium) is a derivative of tanshinone IIA. It acts as an inhibitor of store-operated Ca2+ entry (SOCE) and is used to treat cardiovascular disorders. This product is for research use only and not sold to patients.
- Inhibits store-operated Ca2+ entry (SOCE)
- Used to treat cardiovascular disorders
- Inhibits hypoxia-induced PKG and PPAR-γ downregulation
- Suppresses TRPC1 and TRPC6 expression in hypoxic PASMCs
- Inhibits CYP3A4 activity
- Attenuates scopolamine-induced cognitive dysfunctions
- Alleviates hypoxia-induced characteristic changes in chronic hypoxia PH rat model
- Prevents peritoneal adhesion
eMolecules 568-72-9 | Tanshinone IIA | MFCD00238692 | 100mg
Ambeed | Tanshinone IIA | 100mg | 552521161 | A104838 | 568-72-9 | MFCD00238692 | 294.350 | C19H18O3
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
Sigma Aldrich Fine Chemicals Biosciences Tanshinone IIA United States Pharmacopeia (USP) Reference Standard | 568-72-9 | MFCD00238692 | 20MG
Tanshinone IIA United States Pharmacopeia (USP) Reference Standard | Mol Wt: 294.34 | 568-72-9 | MFCD00238692 | 20MG
Medchemexpress LLC Cucurbitacin IIa | 58546-34-2 | 562.73 | 1 MG
Cucurbitacin IIa, also known as Hemslecin A, is an orally active EGFR inhibitor capable of permeating the blood-brain barrier. It demonstrates an IC50 of 1.455 nM against human EGFR and exhibits anti-inflammatory activity by inhibiting the EGFR-MAPK signaling pathway.
Features and Benefits:
- Induces caspase-3-dependent apoptosis.
- Downregulates survivin expression.
- Enhances autophagy levels.
- Disrupts the actin cytoskeleton via actin aggregation.
- Arrests the cell cycle at the G2/M phase.
- Supports research into inflammation-related diseases.
- Useful in studies on depression and cancers like non-small cell lung cancer.
Medchemexpress LLC 4,4'-sulfonylbis(2-methylphenol) | 16346-97-7 | MFCD00130281 | 97.0% | 278.32 g·mol-1 | C14H14O4S | 25 MG
Topoisomerase IIα-IN-9 is a bisphenol-derived small-molecule inhibitor of human DNA topoisomerase IIα intended for research use. Reported biochemical activity includes Topo II inhibition (IC50 ≈ 571 μM) and cell growth inhibitory activity in K562 and CHO cells (IC50 ≈ 117 μM and 218 μM, respectively). Molecular formula C14H14O4S and molecular weight 278.32 g·mol-1 are provided; consult the Certificate of Analysis for purity and storage conditions.
- Moderate inhibitor of DNA topoisomerase IIα.
- Exhibits cell growth inhibition in selected cell lines.
- Provided as a characterized small molecule with formula and molecular weight.
- Suitable for biochemical assays and cell-based research applications.
- Certificate of Analysis available for purity and handling details.
Apexbio Technology LLC Tanshinone IIA 568-72-9 20mg
Tanshinone IIA (CAS 568-72-9) is a diterpene quinone extracted from the medicinal plant Salvia miltiorrhiza (Danshen) It modulates cellular signaling by inhibiting the binding of transcription factors NF- B and AP-1 to DNA thereby regulating gene expression associated with inflammation and proliferation Tanshinone IIA has demonstrated the capacity to suppress -amyloid aggregation and protect neuronal PC12 cells against -amyloid-induced apoptosis It exhibits both antioxidant and anti-inflammatory properties supporting its use in studies related to oncology neurodegeneration and inflammation
Medchemexpress LLC 4,4'-sulfonylbis(2-methylphenol) | 16346-97-7 | MFCD00130281 | 278.32 g/mol | C14H14O4S | 10 MG
Topoisomerase IIα-IN-9 (4,4'-sulfonylbis(2-methylphenol)) is a bisphenol compound that moderately inhibits human DNA topoisomerase II and reduces cell proliferation in selected cell lines. It is supplied for laboratory research; lot-specific purity, solubility, and storage conditions are provided in the product data sheet and Certificate of Analysis.
- Moderate topoisomerase II inhibition (IC50: 571 μM).
- Inhibits K562 cell growth (IC50: 117 μM) and CHO cell growth (IC50: 218 μM).
- Molecular weight 278.32 g/mol and formula C14H14O4S.
- CAS number 16346-97-7 for unambiguous identification.
- Intended for research use; consult Certificate of Analysis for purity and storage.
Medchemexpress LLC Tanshinone I | 568-73-0 | MFCD00210563 | 98.8% | 276.29 g/mol | C18H12O3 | 10 MG
Analytical standard of Tanshinone I supplied as a high-purity reference material for research and analytical use. It is intended for qualitative and quantitative analysis, method development, calibration, and identity/purity testing by techniques such as liquid chromatography, gas chromatography, and mass spectrometry. Reported purity ≈98.8% and CAS 568-73-0.
- Intended for analytical applications such as LC, GC, and MS.
- High purity suitable for calibration and quantitative analysis.
- Useful for method development and identity and purity testing.
- Available in small research quantities for laboratory use.
Medchemexpress LLC Tanshinone IIA anhydride | 61077-78-9 | 310.34 | 1 MG
Tanshinone IIA anhydride is a potent and irreversible human carboxylesterase (CE) inhibitor. It has Ki values of 1.9 nM for human CE1 and 1.4 nM for human intestinal CE (hiCE).
- Potent and irreversible human carboxylesterase (CE) inhibitor
- Ki values of 1.9 nM for human CE1
- Ki values of 1.4 nM for human intestinal CE (hiCE)
